The Temple Lung Center conducts one of the most comprehensive lung disease clinical trials programs in the country. Our advancements in basic, translational and clinical research are changing lung disease treatment. By pioneering effective therapies, we bring hope to patients with serious and debilitating lung diseases.
Review Our Open Clinical Trials
Asthma
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
NCT05097287
NCT05097287
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/?Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
Pragmatic Open - Label Randomized Clinical Trial of FF/?UMEC/?VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma
A Study to Evaluate Solriktug in Adult Participants With Asthma (RAINIER)
COPD
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
NCT05119556
NCT05119556
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3 (BREATHE-3)
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (EMBARK)
Temple Health Chest Initiative (THCI 2.0) - Lung Cancer Screening Project With COPD Detection
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema (ELEVAATE OLE)
NCT05897424
NCT05897424
STRIVE Post-Market Registry Study
Biological Effects of Quercetin in COPD Phase II
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
Interstitial Lung Disease (ILD)
PH-ILD DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease (BEconneCTD-ILD)
NCT06572384
A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
NCT06335303
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
NCT05943535
SSc-ILD A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (BLISSc-ILD)
NCT05878717
NCT05878717
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients (EGCG-101)
NCT05195918
NCT05195918
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
A Study Evaluating the Safety and Efficacy of AP01 in Participants With Progressive Pulmonary Fibrosis (PPF)
Inpatient
Trial of Therapeutic Hypothermia in Patients With ARDS (CHILL)
Lung Cancer
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening (PROACT-LUNG)
Lung Transplant
A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction (ROCKaspire)
Mesothelioma
National Mesothelioma Virtual Registry and Tissue Bank (U19)
Mycobacterium Avium Complex Disease
ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension (ICoN-1)
Pulmonary Vascular Disease
PH-ILD DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
NCT04798261
Novel alpha2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial (NAIL-IT)
NCT05408546
NCT05408546
PH-COPD MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
NCT05612035
PH-COPD The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
NCT06433011
Sarcoidosis
Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis (KITE)
Other
American Lung Association (ALA) Lung Health Cohort
NCT04543461
NCT04543461